Effects of intraoperative magnesium sulfate administration on postoperative tramadol requirement in liver transplant patients.

Introduction Magnesium is an N-methyl-D-aspartate receptor blocker and it’s known to have analgesic effect [1,2]. Hypomagnesaemia is often seen in major surgery and it is associated with higher morbidity, mortality, organ dysfunction, systemic inflammatory response syndrome and pulmonary hypertension [2,4]. It’s shown that intra-operative use of magnesium sulfate reduced per-operative analgesic requirement [5].